What is the success rate of in vitro fertilization is a question of concern to many infertile couples. Please join the Asianparent to learn specifically about this issue through the content below.
What is in vitro fertilization?
In vitro fertilization, also known as In vitro fertilization (IVF) is an assisted reproductive method for infertile couples where sperm and eggs are combined outside the body. After fertilization occurs, an embryo is formed and then transferred into the uterus. Embryo implements and develops into a fetus similar to a natural conception.
The success rate of in vitro fertilization depends on many factors
In vitro fertilization is one of the methods of choice for infertility treatment. According to medical reports, the success rate is generally quite high.
Previously, embryos were transferred at a stage of 4-8 cells, that is 2-3 days after embryo culture to transfer into the uterus. This technique is less expensive but the success rate is not high, only approximately 25-30%.
Today, with the modern in vitro fertilization method Micro Array, the success rate of this method is up to 80-90%, 3-4 times higher than that of conventional in vitro fertilization technique. The advantage of this method is that it can check up to 23 pairs of chromosomes, eliminating up to 200 types of diseases and genetic defects.
However, this rate can vary depending on factors such as the age, the cause and the psychology of the infertility couple.
What is the success rate of in vitro fertilization depends on many factors
Factors influencing the success rate of in vitro fertilization
Age
Pregnancy and childbirth whether in the form of natural insemination or in vitro fertilization depend greatly on the age of the mother. Because the older a woman's age, the lower the number and quality of eggs that can meet the standards that can be combined with the sperm to form healthy embryos. Especially after the age of 35, the chances of successful conception will decrease and the rate of embryo destruction is also higher when done. The ideal time to give birth is about 20-30 years old, if after 45 years, in vitro fertilization success rate is only about 4%.
With in vitro fertilization, the most important stage is at the extraction of the egg (after the injection of an ovulation stimulant). During the egg stimulation process, the mother will know how many eggs she has in this cycle. The number of eggs for each woman is different, depending on the location of each person. The better the quality of the egg, the more embryos are contaminated, thereby increasing the chances of multiple embryo transfer during one egg stimulation cycle.
In addition, embryos are also classified into type 1, type 2 and type 3 embryos depending on the quality of the embryo. However, the quality of embryos is not too different, so mothers should not be too worried if there are only 2 or 3 embryos without type 1 embryos.
Treatment is in an early stage
All couples are checked for infertility, infertility before conducting in vitro fertilization. For cases of infertility, infertility for many years, the cause of infertility is complicated ( the husband's sperm is too few, too weak ...; or the wife has a history of excessive ovarian stimulation, endometriosis ... This will affect the in vitro fertilization process as well as its success rate and become more difficult, according to hospitals and centers that specialize in implementing this method. is highest when the infertility period is less than 2 years and will decrease when infertility is 6 years or more.
Therefore, as recommended, if after 1 year of not using contraception but there is still no good news, couples should see a doctor to have a better chance of success in early treatment.
Qualifications and techniques for implementation
In vitro fertilization is a complex multi-step technique that requires not only expertise but also experience by the physician and technician. For example, in the process of injecting stimulants, whether the transfer of embryos is successful or not depends largely on the skill and experience of the doctor to be able to choose the appropriate location, with little care. Mildly avoid damaging the endometrium.
Especially in cases where infertility is complicated, the doctor will have to decide whether to perform relevant techniques such as injecting sperm into the oocyte (ICSI), raising young eggs and then fertilizing. crystal ... or not.
Furthermore, the implementation of the correct techniques can help couples save money and time while reducing the risks of the mother's health.
Therefore, parents should look to big hospitals with a team of highly skilled specialists and doctors, recognized by the medical council in the country and internationally to soon have a chance to become a parent.
Nutrition regime and living activities of the couple
Nutrition and activities also play a very important role in affecting the success rate of in vitro fertilization. Parents should note:
Eat a full range of nutrients, increase protein-rich foods such as chicken, beef, pork, oysters, shrimp, crab, milk ..., eat lots of vegetables, fiber, and fruits.
For the wife, from before the treatment should choose foods rich in folic acid (vitamin B9) such as bean sprouts, spinach, whole grains, fresh fruits such as oranges, grapefruit ... and rich foods. omega 3 such as fish oil, vegetable oil ...
Avoid smoking, alcohol or drugs.
Limit sexual intercourse at least 24 hours before transfer and a long time after embryo placement as directed by a doctor to avoid stimulating uterine contractions affecting conception and embryo.
Take a gentle shower with warm water, always clean your genitals, and change your underwear regularly to avoid infection.
Choose gentle exercises, increase resistance like yoga, walking ...
Equipment of the laboratory
For in vitro fertilization, young eggs or embryos, when cultured outside the mother's womb, are susceptible to attacks by bacteria, mold spores, viruses ... in the air, affecting their development. lice stop growing. Therefore, in vitro fertilization requires a laboratory that meets strict standards: sterility, adequate temperature, humidity, air quality is always at its optimum.
It can be said that the clean room standard plays an important role in the success or failure of in vitro fertilization. Up to now, in Vietnam there are not many hospitals and fertility support centers that meet this cleanroom standard, parents should learn carefully to choose an address that meets the conditions. this.
Psychology of the couple
Before the embryo transfer, the wife is often very worried and afraid of the feeling of pain, so her spirit is sometimes unstable. Therefore, before the embryo transfer, both husband and wife and especially the wife must keep a comfortable and relaxed mentality. Can plan travel. If a woman has psychological instabilities that will lead to a strong uterine contraction, the embryo is difficult to implant when transferred into the uterus. Therefore, absolutely should not let the wife be sad, worried and think a lot. If so, the process of in vitro fertilization has a high success rate.
Do not suffer from sexual diseases
When deciding to implement this method, both husband and wife, especially the wife, need to be sure not to have sexually transmitted diseases. Before the procedure of in vitro fertilization, the couple will be checked to see if they are healthy enough to perform. If the woman's health is normal, the man's sperm is healthy, the chance of success will be very high.
BMI of the body
BMI is the body mass index, used to assess whether a person's body is thin or fat by weight and height.
Doctors pay special attention to the BMI when administering ovarian stimulants to a wife during in vitro fertilization. If the wife is too fat, the egg stimulant will be used at a higher dose, longer because the ovaries often work less effectively than normal people. Moreover, if the woman is too obese to become pregnant, the baby can be born with obesity or diabetes.
Conversely, if a woman is too thin, the risk of miscarriage will be high.
Therefore, control of body weight is a very important factor in the success rate of in vitro fertilization.
Up to now, in vitro fertilization is currently the highest success rate of any fertility technology. It is also a solution that brings a lot of hope for infertile and infertile couples after having performed other fertility methods such as unsuccessful use of stimulants or artificial insemination. In vitro fertilization success rate largely depends on the couple themselves. Therefore, couples need to maintain good health as well as find out and choose a reliable address to increase the probability of success on the journey of "looking for a baby".
see more
Safe and scientific nursing for mothers WITH TUBE
IN-TUBE (IVF) CLEANING PROCEDURE; The infertility couple need to know!
For mothers doing IVF; What to eat after embryo transfer?