A 2-year-old boy in Phu Tho is given a 500-mg antipyretic drug Paracetamol by his family at a dose of 4 tablets / day for 4 days. After hospitalization, the baby fell into a coma, the risk of death.
On August 14, the Emergency Department, Obstetrics and Pediatrics Center, Phu Tho General Hospital, received a 27-month-old pediatric patient with signs of Paracetamol poisoning due to overdose.
Family members said that the baby has high fever, wheezing cough should be given a dose of 500 mg Paracetamol fever-reducing drug at a dose of 4 tablets / day for the past 4 days.
Children hospitalized in a state of drowsiness, fatigue, fever 38 degrees, shortness of breath, wheezing, tachycardia, poor ventilation, enlarged liver 2 cm below the ribs. Doctors diagnose severe metabolic acidosis respiratory failure in pediatric pneumonia, monitoring Paracetamol poisoning.
After receiving the first aid from the first aid doctor, the child was transferred to the intensive care unit - Anti-poison.
Here, the baby was placed in endotracheal tube, mechanical ventilation, gastric lavage, alkaline compensation.
Two hours after being admitted to the hospital, the baby fell into a coma, the pupils on both sides contracted, poor light reflection, tachycardia, blood pressure drop, symptoms of acute liver failure, severe coagulation disorder, elevated liver enzymes. Bilirubin soared.
Doctors evaluated this as a serious illness, prognosis of death without liver transplantation. After adjusting to basic life functions, the baby was transferred to the National Hospital of Pediatrics (Hanoi) for further treatment.
MSc, doctor Phan Hong Sang - Deputy Head of the Department of Active Resuscitation - Anti-Poisoning - Center of Obstetrics and Pediatrics - said that a year ago, doctors also accepted cases of 3-year-old children who died from drug poisoning. This paracetamol.
When your baby has a high fever of 38.5 degrees C or higher, the fever reducer will be given to him. Do not exceed 1,000 mg / day (4 packs of 250mg) with children. When using for children must calculate the dosage (or according to the specific instructions of the doctor). Note to parents, if after 48 hours the child is still sleepy, vomiting a lot, they need to see a doctor immediately!
Unlike adults, because children are special subjects, children are given a dosage that is usually calculated on the drug mg / kg weight of the child. Specifically, on 1 weight of a child, only 10-15mg of paracetamol / kg each time. Depending on the child's weight, mothers will calculate the dose for each use, for example, children weighing 10kg will use 100-150mg of paracetamol each time. Based on the child's weight is also a smart and popular way of calculating the dosage of antipyretics for children that mothers often use.
Although the dose of paracetamol each time for children of all ages is 10-15mg / kg, but the number of times used for a whole day is 24 hours, depending on the child's age. For example, infants use 10-15mg / kg each time and with a frequency of 6-8 hours, using it once, that means 3-4 times a day.
For older children, use the same dose as an infant, but the dose is closer, every 4-6 hours, ie 4-6 times / day, but it is best not to use more than five times in 24 hours.
Based on the child's age to calculate the dose of fever-reducing medicine is also a way of calculating the dose of fever-reducing medicine for the baby, mothers need to keep in mind, because at different ages, the level of medicine for children is also different.
This is a separate calculation for highly toxic drugs like cancer drugs. In fact, in hospitals, specialists rely on the child's weight and height as well as based on formulas or spreadsheets available to deduce the child's skin area and from there calculate the dose of medicine. Although this is the most accurate calculation, it is quite complicated, doctors have to do it for the safety and effectiveness of the drug on children.
According to doctors, especially with paracetamol which is a medicine or used to reduce fever for children, it is recommended to apply the method of calculating the dose of fever-reducing medicine for children by weight and using liquid medicine. Health experts recommend that it is best not to take adult paracetamol tablets or split 1/2, 1/3, 1/4 ... tablets for use in children.
Observe a safe distance between 2 doses to avoid overdose, which can affect health. Only repeat the next dose after 4 hours if the child has a fever, usually 3-4 times a day. The maximum total dose should not exceed 60mg / kg in 24 hours.
In the home medicine cabinet should keep 2 different antipyretic drugs in the form of powder and suppository. Powder package form usually has a sweet taste, aroma of fruit, suitable for children's preferences, quickly reducing fever effect, only about 15-30 minutes after drinking.
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